Plastics & Products

White Pharmaceutical Raw Materials 24065-33-6 Rivaroxaban Intermediate

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Product Info :

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Molecular Formula: C5H3ClO2S
CAS Registry Number: 24065-33-6
Usage:An intermediate of Rivaroxaban .

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About Rivaroxaban :


Rivaroxaban and dabigatran etexilate are currently the most promising antithrombotic drugs, and compared to traditional antithrombotic drugs heparin, essential difference is that it does not require participation of antithrombin Ⅲ, directly antagonizes the free and bound Xa factor. And heparin needs to have antithrombin Ⅲ and can play a role, and is invalid to the prothrombin complex of Xa factor. Two new oral anticoagulants are praised as as a major step forward of anticoagulant therapy and potentially fatal thrombosis prevention in the medical field, will become a new milestone in the development of cardiovascular drugs.

Rivaroxaban is the world& acute;s first oral direct Xa factor inhibitor, can be high selectively, competitively inhibit free and bound Xa factor and activity of prothrombin, in a dose - dependent manner prolonged activated partial thromboplastin time board (PT) and prothrombin time (aPTT), thus prolonging the clotting time, reducing thrombin formation. Having characteristics of high bioavailability, a wide spectrum of disease treatment, dose effect relationship is stable, convenient oral administration, low bleeding risk.

Rivaroxaban also is drug for prevention and treatment of venous thrombosis. Clinically for the prevention of forming patients with deep vein thrombosis (DVT) and pulmonary embolism (PE) after hip joint and knee replacement surgery. It can also be used to prevent stroke and non-CNS systemic embolism in patients with non-valvular atrial fibrillation, reduce the risk of recurrent coronary syndrome, and so on.

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Packaging:


(1) 10g/100g/500g/1kg, packaged by Aluminum foil bag.
(2) Customized package.

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Chemical Properties:
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Appearance | ?Off white powder |
Molecular Weight | 162.59 |
Molecular Structure | |
Density | 1.572 g/cm3 |
Boiling Point | 287 °C at 760 mmHg |
Flash Point | 146-150℃ |
Refractive index | 127.4 °C |
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Safety Information:

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Hazard Codes | [Xi] |
Risk Statements | [36-43-36/37/38] |
Safety Statements | [26-36-37/39] |
WGK Germany | 3 |
RTECS | XM8400000 |
Hazard Note | Irritant |
HazardClass | IRRITANT |
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FAQ:
Q1: Are you a manufacturer?
A: Yes, We manufacture bulk products in our factory located in Jiayu, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan.
Q2: Do you have stock?
A: We understand most customers prefer stock, so we& acute;ll try to keep stock for most products. However, for some rare products, we won& acute;t keep stock and it needs time to synthesize.
Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.
Q4: Why should I choose you?
A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5 years, in average.
Strict quality control-comes form our sophisticated management system.
Professional and warm sales team-since we believe we can only win via our hard work in a competitive world
Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service
Q5: Can I get best price from you?
A: Of course. We don& acute;t chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don& acute;t make it too hard!
Q6: How should I pay?
A: We accept all kinds of payment ways. such as alibaba trade asssurance, T/T, West union, Paypal.
Q7: Do you provide free sample?
A: Yes, we can provide free sample if we have in stock, just need you to cover the delivery cost.