White Crystalline Powder Pharmaceutical Intermediates Trilostane Cas 13647-35-3 - 13647-35-3
White Crystalline Powder Pharmaceutical Intermediates Trilostane Cas 13647-35-3 For Sale, Most Competitive Price, Fast Delivery, Custom Service, Wholesale White Crystalline Powder Pharmaceutical Intermediates Trilostane Cas 13647-35-3, Made in China, High Quality Products!, China Steroids, chemical Supplier, Manufacturer.
White Crystalline Powder Pharmaceutical Intermediates Trilostane Cas 13647-35-3
Basic Info.
Trilostane
Synonym: Vetoryl
CAS : 13647-35-3
Molecular Formula: C20H27NO3
Molecular Weight: 329.4333
Assay :99%
Einecs No: 237-133-0
Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Appearance:: White crystalline powder
Usage : Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism. This product also had significantly effect to decreased serum testosterone level.
Product Description:
Trilostane is used in the treatment of Cushing& acute;s syndrome. It is normally used in short-term treatment until permanent therapy is possible. Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing& acute;s syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.
Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5,4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids.
Side effect:Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.
Application:
Trilostane can suppress cortical hormone synthesis process of 3 beta dehydrogenase, make cortisol, aldosterone synthesis reduce, clinical used in the treatment of Cushing syndrome(cortisol increase disease) and primary aldosteronism,the effect is not good than testosterone metyrapone. This product has significantly reduced blood testosterone level role, may relevant to its inhibit synth
Guangzhou Kafen Biotech Co., Ltd.
Address: No. 128, Hanxing East Rd, Zhongcun, Panyu District,, Guangzhou, GuangDong, China, 511495
Tel: +8618022403273
Guangzhou Kafen Biotech Co., Ltd is a high-tech and professional company founded in 2002, which specialized in developing, manufacturing, distributing steroid hormone powders and intermediates. We have been devoted in R&D, production and marketing steroid hormone and pharmaceutical raw materials.
With advanced production technology and equipment, strong technical force, first-class laboratory and inspection equipment. Kafen has developed into a professional factory manufacturing anabolic steroid powders with several years'efforts and contribution of experienced technicians in different areas. Company affiliated factory has advanced production equipment and plants, perfect quality assurance and control system, whole set of High Pressure Liquid Chromatography/Gas Chromatography/UV Spectrophotometer to conduct effective product analysis and monitoring. Company factory has passed ISO9001 quality system certification and international KOSHER certification.
Now, we continues its high speed development and contributes a lot to its new products' R&D and quality improvement. Under the credibility and win-win principle, kafen biotech will devote to culture innovation to provide excellent products and best service to our customers.
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