Small Molecular API Cediranib (CAS: 288383-20-0), China Small Molecular API Cediranib (CAS: 288383-20-0) Supplier

Small Molecular API Cediranib (CAS: 288383-20-0) - 288383-20-0

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(CAS: 288383-20-0)

Chemical Information
Product Name Gefitinib hydrochloride
Molecular Formula C22H25Cl2FN4O3
Molecular Weight 483.36

Description
The EGFR is a Mr 170,000 transmembrane glycoprotein with an external binding domain and an intracellular tyrosine kinase domain. Gefitinib (ZD-1839, Iressa) is an Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor.

Dosage
Administration of a 250-mg dose of gefitinib as a dispersion preparation by drink or nasogastric tube achieved a systemic exposure to gefitinib that was consistent with that achieved when gefitinib was administered as a whole tablet. No evidence of tolerability problems associated with the routes of administration studied was observed in these healthy volunteers.

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