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Quick Detail:

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# Produce Name: Gamma-Butyrolactone(GBL)
# Synonyms: Gamma Butyrolactone, 1, 4- Butyrolactone, γ -Butyroladone, GBL, BLO,
# CAS number: 96-48-0
# EINECS number: 202-509-5
# Formula: C4H6O2
# M. W.: 86.09
# Packing: In 180litres net iron drum or 25litres plastic drum



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Uses:



(1) GBL can be used to produce a-pyrrolidone, 1-Methyl-2-pyrrolidinone , polyvinyl pyrrolidone, and α-Acetyl-γ-butyrolactone, etc.

(2)GBL can be used as anaesthetic and tranquilizer, used to produce ciprofloxacin and interferon, as the intermediate of vitamin and rolicyprine;

(3) GBL is the intermediate of plant growth stimulator and insecticide.

(4)GBL is a good antioxidant, plasticizer, extractant, adsorbent, dispersant, fixative and curing agent; Moreover, it can also be used in battery, capacitor and development of color film.

Product Description:


Gamma-Butyrolactone (γ-butyrolactone or GBL) is a hygroscopic colorless liquid with a weak characteristic odor which is soluble in water. GBL is a common solvent and reagent in chemistry as well as being used as a flavouring, as a cleaning solvent, as a superglue remover, and as a solvent in some wet aluminium electrolytic capacitors. In humans it acts as a prodrug for GHB, and it is used as a recreational intoxicant with effects similar to alcohol.

GBL has been found in extracts from samples of unadulterated wines.[3] This finding indicates that GBL is a naturally occurring component in some wines and may be present in similar products. The concentration detected was approximately 5 μg/mL and was easily observed using a simple extraction technique followed by GC/MS analysis. GBL can be found in cheese flavourings but typically results in a content of 0.0002% GBL in the final foodstuff.

GBL is a lactone. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium gamma-hydroxybutyrate, the sodium salt of gamma-hydroxybutyric acid. Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer. When treated with a non-nucleophilic base, like lithium diisopropylamide, GBL can become an alpha-carbon nucleophile. The related compound caprolactone can be used to make a polyester in this manner.
GBL is not active in its own right; its mechanism of action stems from its identity as a prodrug of GHB.
The hypnotic effect of GHB is enhanced by combination with alcohol. A 2003 rat study showed that GBL in combination with ethanol showed a potentiated hypnotic effect, as the sleep-timing measure was longer than both of the individual components combined

GBL is rapidly converted into GHB by paraoxonase (lactonase) enzymes, found in the blood.[7][8] Animals which lack these enzymes exhibit no effect from GBL.[7] GBL is more lipophilic (fat soluble) than GHB, and so is absorbed faster and has higher bioavailability. Because of these pharmacokinetic differences, GBL tends to be more potent and faster-acting than GHB, but has a shorter duration; whereas the related compound 1,4-butanediol (1,4-B) tends to be slightly less potent, slower to take effect but longer-acting than GHB.

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Product name | Butyrolactone |
Other name | ? |
EINECS | 202-509-5 |
Molecular formula | C4H6O2 |
Molecular weight | 86.09 |
Melting point | -45degree |
Assay | 100% |
Appearance | transparent liquid |
Package | Discreet |
Usage | can be used as pharmaceutical material |
Minimum order quantity | 1L |
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Application:


1)it is Used to produce a-pyrrolidone, 1-Methyl-2-pyrrolidinone, polyvinyl pyrrolidone, and α -Acetyl-γ -butyrolactone;
2) it is used as anaesthetic and tranquilizer, used to produce ciprofloxacin and interferon, as the intermediate of vitamin and rolicyprine;
3) As antioxidant, plasticizer, extractant, adsorbent, dispersant, fixative and curing agent;
4) it is Used in battery, capacitor and development of color film.


Packaging & Delivery Process:


We have sufficient stock, so we can delivery promptly at the very day when receive the payment We also own sophisticated and professional logistic agent. We take responsibility to provide our customers with fast delivery and secure shipping

Packing pictures and tacking code would be provided within 12 hours after receiving the payment. Updated tracking information will be provided every other day.

We provide helpful after-sale service: Any questions or problems after receiving the product, please feel free to contact us. Problems would be solved immediately.

Competitive Advantages:
ShangHai ShuCan Industrial Co,LTD is a renowned pharmaceutical manufacturer, specializing in safe organic solvents in Mainland China.
Our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries..
Top quality products with the most competitive rate. Free samples are available.
Flexible and reliable payment terms

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Keywords:

Safe Organic Solvents
Pharmaceutical Intermediates;
Heterocycles;
Miscellaneous Reagents