Chemicals Agents

SARMS Selective Androgen Receptor LGD4033 Ligandrol 1165910-22-4 Human Performance Enhancement

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LGD-4033 is a selective androgen receptor modulator (SARMS), and a novel non-steroidal oral SARM that binds to AR with high affinity (Ki of ~1 nM) and selectivity. It& acute;s in a class of androgen receptor (AR) ligands that is tissue selective, developed to treat muscle wasting associated with cancer, acute and chronic illness and age-related muscle loss.

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1. Quick Details:

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Product Name:LGD4033
Chemical name:4-((R)-2-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-trifluoroMethyl)benzonitrile
CAS No.:1165910-22-4
MF:C14H12F6N2O
MW:338.25
Purity:99.2%
Product categories:SARMs(Selective androgen receptor modulator)
Appearance:White crystalline powder
LGD-4033 Usage:A Potent, Non-Steroidal Bodybuilding Supplement

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2. Description:

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LGD-4033 is a selective androgen receptor modulator (SARMS), and a novel non-steroidal oral SARM that binds to AR with high affinity (Ki of ~1 nM) and selectivity. It& acute;s in a class of androgen receptor (AR) ligands that is tissue selective, developed to treat muscle wasting associated with cancer, acute and chronic illness and age-related muscle loss. LGD-4033 is expected to produce the therapeutic benefits of testosterone with improved safety, tolerability and patient acceptance due to tissue-selective mechanism of action and an oral route of administration.

LGD-4033, a novel nonsteroidal, oral selective androgen receptor modulator, binds to the androgen receptor with high affinity and selectivity. It demonstrates anabolic activity in muscles, anti-resorptive and anabolic activity in bones and a robust selectivity for muscle and bone versus prostate and sebaceous glands. LGD-4033 has recently completed a Phase I Multiple Ascending Dose study in healthy volunteers. This randomized, double-blind, placebo-controlled Phase I study established the safety and tolerability up to doses of 22 mg per day.

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3. Application:

LGD is still fairly new (3-5 years), but the results have been very similar in studies and logs. LGD-4033 has undergone several recent studies and trials to find the best and safest way to use it. From these trials, the results have shown increases in lean body mass and decreases in body fat. There is also a significant increase in strength, well being, as well as healing possibilities.

LGD has shown the most ability of any SARM to put on size that could be considered a bulk. This will, of course, be dependent upon the diet used. Users that have experienced more than 10lb. increases, and have had a significant increase in calorie intake. The possibility of this type of size is present with LGD use. A recommend dosage for this type of goal would be 5-10 mg day for 8 weeks.

LGD seems to shine with this method. Many have seen an increase in lean body mass and a decrease in body fat. LGD seems to work the best with this method. Ran in conjunction with other SARMS, like cardarine (GW-501516), will only increase the likelihood of a stronger recomp. Recommended doses for recomping would be 5-8 mg a day for 8 weeks.

LGD can be used to cut as well. It will shine more-so if ran in conjunction with SARMS S-4 and Cardarine (GW-501516). This would be similar to a SARMS triple stack that is normally ran with Ostarine, except there is a possibility of more size being put on while cutting. A good dose for this method would be 3-5 mg a day for 8 weeks.

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4. Related Question:

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1) What Is LGD-4033 ?


LGD-4033 is rapidly increasing in popularity, as it has shown to be the strongest and most anabolic-like SARM in existence up to this point. SARMS are quite different from steroids in terms of their makeup, lack of side effects and recovery time. SARMS can be run much longer than oral steroids. They are non-methylated and don& acute;t pressure the liver. Although the results are not as drastic as some steroids, they are much cleaner, more keepable and have several properties that are extremely desirable that steroids may not be able to provide.

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2) Why We Need LGD-4033?

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The problem with kick-starting is that oral steroids are highly methylated and come with their fair share of side effects. In fact, methylated orals can cause damage to your liver, blood pressure, cholesterol, lipids, kidneys, organs, etc. In addition, methylation can cause lethargy and become even more of a detriment, draining a user of their motivation and desire to do much of anything. There are excellent products that provide protection against this, N2Guard is a good example. However, when you are running a cycle, you want to not only get the highest amount of gains possible, but you also want to feel as though you are on top of the world. You SHOULD be feeling that way throughout. This is where LGD-4033 becomes such a wonderful option for a user.

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3) What Is the Side effect ?

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Through studies and logs, the side effects from LGD have so far shown to be minimal. The suppression shown has been dose dependent, but there has been a decrease in total and free testosterone as well as SHBG. These interesting findings have show NO significant decrease in LH or FSH. This is very encouraging to users as it shows that while suppressive, recovery will still not be near as long as with anabolic steroids. LGD is non toxic and side effects have been mild to minimal. It has not shown increases in estradiol ,but, as with anything, an aromatase inhibitor should be kept on hand.

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5.?COA:

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Test Items | Standards | Results |
Description | White crystalline powder | Conforms |
HNMR | H group on the peak of the correct attribution | Conforms |
Loss on drying | Not more than 0.5% | 0.3% |
Heavy metals | Not more than 10ppm | Not more than 10ppm |
Assay(HPLC) | More than 98% | 99.2% |
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Conclusion : | Compliance with the requirements |
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6. Related Product:

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Name | CAS NO. | Usage |
AICAR | 2627-69-2 | acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown |
MK2866 | 841205-47-8 | medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testoserone Replacement Therapy. |
MK-677 | 15972-10-0 | A growth hormone secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly |
LGD-4033 | 1165910-22-4 | pharmacological profile similar to that of enobosarm, Ostarine,MK-2866 |
GW1516 | 317318-70-0 | For obesity, diabetes, dyslipidemia and cardiovascular disease |
Andarine(S4) | 401900-40-0 | partial agonist, intended mainly for treatment of benign prostatic hypertrophy |
SR9009 | 1379686-30-2 | under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice |
RAD140 | 1182367-47-0 | New generation for gaining mass and cutting edges |
YK11 | 431579-34-9 | YK11: a SARM and myostatin inhibitor in one |
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7. Competitive Advantages:

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Rich experience:
We specialize in this field for many years,our pharmaceutical raw materials exported to Overseas, to Europe,Africa,Asia, Americas and other country, and we have got very good feedback from our customers,and Established long friendly relations of cooperation.
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Safest and fastest delivery:
We have Adequate stock,and can arranged within 24 hours when receive the payment.Tracking number would be informed quickly after shipment.
We have special way could ship 2kg to 20tons products a time. We offer melting powder into liquid service.And ship the liquid in special bottles.


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Tell the package update asap, and will try best solve when customer encountered various problems!


Everything is for customers:
Our products and services will focus on the largest customer demand,We hold the greatest enthusiasm and sincere cooperation with each customer.
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