Rifabutin 72559-06-9 - NO

Rifabutin 72559-06-9 For Sale, Most Competitive Price, Fast Delivery, Custom Service, Wholesale Rifabutin 72559-06-9, Made in China, High Quality Products!, China API Inhibitors, pharmaceutical Supplier, Manufacturer.
Rifabutin 72559-06-9

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Product Description

Molecular Weight: 847 Rifabutin is a semisynthetic ansamycin antibiotic, used in the treatment of Mycobacterium avium intracellulare (MAI) and tuberculosis.
Biological Activity

Rifabutin has a broad spectrum of antimicrobial activity. Rifabutin is considerably more active than rifampin in vitro against the Mycobacterium avium complex (MAC), Mycobacterium tuberculosis, and Mycobacterium leprae. Rifabutin also is active against most atypical mycobacteria, including Mycobacterium kansasii, but Mycobacterium chelonae is relatively resistant. Rifabutin also is active against staphylococci, group A streptococci, Neisseria gonorrhoeae, Neisseria meningitidis, Haemophilus influenzae, Haemophilus ducreyi, Campylobacter jejuni, Helicobacter pylori, Chlamydia trachomatis, and Toxoplasma gondii.

Rifabutin shows an isoenzyme-selectivity profile similar to that produced by Rifampicin, but the maximally achievable induction of cytochrome P-450 3A by Rifabutin is about two-fold lower compared with Rifampicin. Rifabutin enhances the glucuronidation of 1-naphthol, 4-hydroxybiphenyl and beta-estradiol by a factor of two to three.
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Taizhou Crene Biotechnology Co., Ltd cooperate with R & D centers in famous university and GMP manufacture plants. we carry out scientific management. Company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-known enterprises and research institutions. To the workshop from the laboratory-scale production, with good conditions for the custom synthesis can be achieved from gram to ton-class custom synthesis services.The implementation of these projects in the process, we formed a professional and efficient project management system and team, with a strong technical reserves and core competitiveness. www.crenelab.com

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