Pharmaceutical Chemicals

Character White Powder
Molecular Formula C19H23N3O3
Assay 98%

MOQ: 10 g

Quick Details 
Product Name:Coluracetam / MKC-231
Assay:98% Min
Molecular Formula:C19H23N3O3
CAS Registered No.:135463-81-9
Molecular Weight:341.4042
Standard:USP:SGS,ISO9001,KOSHER
Appearance:White Powder
Usage:Gain muscle and lean mass
Packaging Details:1-2 kg / aluminum foil bag,25kg/ drum,as required
What is Coluracetam (MKC-231)
Coluracetam (MKC-231) is a synthetic Racetam drug purported to be a Nootropic compound. It does not have a large body of evidence investigabagg it,but the mechanisms of action (as well as structute) appear to be very disbagct from other racetam compounds like Piracetam or Aniracetam.
Coluracetam appears to interact with a process known as high affinity choline uptake (HACU for short),which is the rate-limibagg step of drawing choline into a neuron for synthesis into the neurotransmitter acetylcholine. Increasing the HACU rate appears to increase the activity of cholinergic neurons,so it is a desired target for cognitive enhancement.
Interventions in rats (as there is no human evidence currently) support the usage of coluracetam at very low oral doses to preserve HACU that is otherwise impaired by the use of research drugs that are known to impair HACU. The limited evidence looking at the inherent effects of coluracetam on the HACU of normal neurons has failed to find any significant interaction.
Coluracetam has also been noted to associate with choline transporters physically,but it is not known exactly what it does once associated.
Overall,there is currently insufficient evidence to support the usage of coluracetam for cognitive enhancement. Further studies are needed to see if it has a therapeutic role in instances where HACU may be impaired (such as Alzheimer's disease).
Descriptions and Applications:
Coluracetam is a nootropic drug of the racetam family. Coluracetam was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD),after being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California. Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD). BrainCells Inc is currently out-licensing the drug for this purpose. It may also have potential use in prevention and treatment of ischemic rebagopathy and rebagal and optic nerve injury.
Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limibagg step of acetylcholine (ACh) synthesis,and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasbagg procognitive effects by changing the choline transporter regulation system.
Origin:China
Export Markets:Global
Packing Method:1 kg/ Aluminum Foil Bag or as Your Requirement
Shelf life:2 years
Storage:keep cool and dry,away from light
MOQ:10 g
Production Capacity:5000 kg/ month
Delivery Time:Within 24 hours After Payment
Shipping Method:EMS,DHL,FedEx,TNT,Express Courier.
Price:negotiable
Payment Terms:Western Union,MoneyGram,Wire Transfer,
Specification:ISO9001,USP,BP
Port:Shenzhen / Shanghai,China
More details pls contact:Whatapp:86 18602752852  
Skype/E-mail:Frank@carnosschem.com
Competitive Advantage: 
1. High quality with competitive price:
1) Standard:Enterprise Standard
2) All Purity≥98%
3) We are manufacturer and can provide high quality products with factory price.
2. Fast and safe delivery:
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,and we have stock in there for transferring.
3. We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease,adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated,meebagg customers's requirement is our responsibility.
3) High quality,competitive price,fast delivery,first-class service gain the trust and praise from the customers.

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