U-47700 For Sale
Post Time: 2017-12-04U-47700 For Sale, Most Competitive Price, Fast Delivery, Custom Service, Wholesale U-47700, Made in China, High Quality Products!, China U-47700 Supplier, Manufacturer.
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U-47700, street name pinky or pink, is an opioid analgesic drug developed by a team at Upjohn in the 1970sthat acts as a selective agonist of the µ-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the κ-opioid receptorand has around 7.5 x the potency of morphine in animal models
U-47700 is a structural isomer of the earlier opioid AH-7921and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. Upjohn looked for the key moieties which gave the greatest activityand posted over a dozen patents on related compounds, each optimizing one moiety until they discovered that U-47700 was the most active.
U-47700 became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures. Although not used medically, the selective kappa ligands are used in research.
Emily Yang
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Our company is always adhering to the ""open, flexible; integrity, and win-win"" business purposes and under the guidance of Business philosophy: ""keeping credit, value quality, punctual delivery, favorable price “, continuously developing the excellent products, improving the service quality, putting efforts to expand the international market, we are committed to provide the excellent quality of products and the perfect services to the friends all over the world. We welcome all merchants to visit our company and talk over business with us!
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