Polypeptide Hormone Follistatin 315 Antibody Fst-315 - kafen

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Polypeptide Hormone Follistatin 315 Antibody Fst-315


Polypeptide Hormone Follistatin 315 Antibody Fst-315


Basic Info.

Specification: 1mg/vial
Purity: 85%+
Appearance : White powder
Specific Optical Rotation (c=0.5,10% HAc) :-50.0~-60.0°
Water Content(Karl Fischer) : ≤5.0%
Acetate Content(by HPLC) : ≤15.0%
Amino Acid Composition : ±10% of theoretical
Purity (by HPLC) :≥98.0%
Single Impurity(by HPLC) :≤1.0%
Peptide Content(by %N) : ≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins : ≤5EU/mg
Storage/Stability: Stored at -20 °C if preferred. Storage in frost-free freezers is not recommended.
Note:This product is furnished for LABORATORY RESEARCH USE ONLY. Not for diagnostic or therapeutic use.


Description of Follistatin:

Follistatin is being studied for its role in regulation of muscle growth in mice, as an antagonist to myostatin (also known as GDF-8, a TGF superfamily member) which inhibits excessive muscle growth. Lee & McPherron demonstrated that inhibition of GDF-8, either by genetic elimination (knockout mice) or by increasing the amount of follistatin, resulted in greatly increased muscle mass.In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength. This research paves the way for human clinical trials, which are hoped to begin in the summer of 2010 on Inclusion body myositis.
A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy (SMA) in animal models.
It is also being investigated for its involvement in polycystic ovary syndrome (PCOS), though there is debate as to its direct role in this infertility disease.


Application:

Follistatin 315 primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.

Storage Instruction
Store at +4°C or at -20°C if preferre

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Address: No. 128, Hanxing East Rd, Zhongcun, Panyu District,, Guangzhou, GuangDong, China, 511495
Tel: +8618022403273
Guangzhou Kafen Biotech Co., Ltd is a high-tech and professional company founded in 2002, which specialized in developing, manufacturing, distributing steroid hormone powders and intermediates. We have been devoted in R&D, production and marketing steroid hormone and pharmaceutical raw materials. With advanced production technology and equipment, strong technical force, first-class laboratory and inspection equipment. Kafen has developed into a professional factory manufacturing anabolic steroid powders with several years'efforts and contribution of experienced technicians in different areas. Company affiliated factory has advanced production equipment and plants, perfect quality assurance and control system, whole set of High Pressure Liquid Chromatography/Gas Chromatography/UV Spectrophotometer to conduct effective product analysis and monitoring. Company factory has passed ISO9001 quality system certification and international KOSHER certification. Now, we continues its high speed development and contributes a lot to its new products' R&D and quality improvement. Under the credibility and win-win principle, kafen biotech will devote to culture innovation to provide excellent products and best service to our customers.

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