Biochemical

Quick Detail:
Product Name:Orlistat
CAS NO: 96829-58-2
Molecular Formula: C29H53NO5
Molecular Weight: 495.73
H bond acceptors: 6
H bond donors: 1
Freely Rotating Bonds: 23
Polar Surface Area: 72.91 ?2
Index of Refraction: 1.469
Molar Refractivity: 141.57 cm3
Molar Volume: 507.5 cm3
Surface Tension: 35.6 dyne/cm
Density: 0.976 g/cm3
Flash Point: 326.3 °C
Melting Point: <50 °C
Enthalpy of Vaporization: 91.36 kJ/mol
Boiling Point: 615.9 °C at 760 mmHg
Vapour Pressure: 4.23E-15 mmHg at 25°C
Storage temp: 2-8°C
Solubility: DMSO: 19 mg/mL
Appearance: Off-White Solid.
Description
Orlistat is a drug designed to treat obesity. It is mainly used for preventing the absorption of fats from the human diet, thereby reducing caloric intake. Besides, it is intended for use in conjunction with a physician-supervised reduced-calorie diet.
Orlistat is a drug that promotes loss of weight by preventing the digestion and absorption of fat in food. In the intestine, an enzyme called lipase (produced primarily by the pancreas) breaks apart fat in food so that it can be absorbed into the body. Orlistat blocks the action of lipase and thereby prevents the breakup and absorption of fat. Orlistat blocks absorption of about 25% of the fat in a meal. The unabsorbed fat is excreted in the stool. The FDA approved Orlistat by prescription in 1999. alli, a lower dose formulation of orlistat, was approved for purchase without a prescription & quot;over the counter& quot; in 2007.