letrozole CAS NO: 112809-51-5 - CAS NO: 112809-51-5

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letrozole CAS NO: 112809-51-5

letrozole
CAS NO: 112809-51-5
Systematic (IUPAC) name: 4,4& acute;-(1,2,4-triazol-1-ylmethyl)dibenzonitrile
Trade names: Femara
MF:C17H11N5
MW:285.3
Content: 99%
Molecular Formula: C17H11N5
Mol. mass: 285.303 g/mol
Quality standard: USP29
Apperance: white or off-white crystalline powder
Packing: 1kg/tin
Storage: shading, confined preservation.
Letrozole (INN, trade name Femara) is an oral non-steroidal aromatase inhibitor for the treatment of hormonally-responsive breast cancer after surgery.
Tamoxifen is also used to treat hormonally-responsive breast cancer, but it does so by interfering with the estrogen receptor. However, letrozole is effective only in post-menopausal women, in whom estrogen is produced predominantly in peripheral tissues (i.e. in adipose tissue, like that of the breast) and a number of sites in the brain. In pre-menopausal women, the main source of estrogen is from the ovaries not the peripheral tissues, and letrozole is ineffective.

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Founded in 2012, Hubei Zhaoke Bio-Chemical Co., Ltd.is a high-tech enterprise which is specialized in the development, production and marketing of steroid hormone APIs & intermediates.Is set branch, industrial and trade an all-around company. The main products of zhaoke are steroid hormone APIs (e.g. sex hormones, progestational hormones and cortical hormones) & intermediates. And zhaoke possesses the leading technology at home and abroad.The quality of the products conforms to updated EP, USP and CP, and the in-house specifications are continually improving. The company possesses of advanced manufacturing processes, robust technologies and first-class analytical instruments. It strictly conforms to the Good Manufacturing Practices (GMP) for all the products in its production and management. The products sell well in many countries, including the United States, Japan and Europe, praised by customers at home and abroad, and achieved good reputation. We welcome all kinds of cooperation with the friends all over the world.

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letrozole CAS NO: 112809-51-5

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