L-2-Aminobutyric acid, CAS 1492-24-6 - 1492-24-6

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L-2-Aminobutyric acid, CAS 1492-24-6

What is L-2-Aminobutyric acid?
In biochemistry, L-2-Aminobutyric acid is also known as homoalanine. It is a non-proteinogenic alpha amino acid. The straight two carbon side chain is one carbon longer than alanine, hence the prefix homo-.
L-2-Aminobutyric acid is an isomer of the amino acid aminobutyric acid. It has two other isomers, gamma-aminobutyric acid (GABA) and beta-aminobutyric acid. In contrast, GABA is a neurotransmitter and not used in protein synthesis, and it is almost always referred to as GABA.

Application of L-2-Aminobutyric acid
L-2-Aminobutyric acid is an intermediate for medicine.

Synthesis of L-2-Aminobutyric acid
Homoalaine is biosynthesised by transaminating oxobutyrate, a metabolite in isoleucine biosynthesis. It is used by nonribosomal peptide synthases. One example of a nonribosomal peptide containing homoalanine is ophthalmic acid, which was first isolated from calf lens.

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