Pharmaceutical Products

Specifications

Ibuprofen 15687-27-1
CAS:15687-27-1
assay:>99%
appearance:white powder

Ibuprofen 15687-27-1
CAS:15687-27-1
assay:>99%
appearance:white powder

Test items
Specifications
Results
Apperance
White crystalline powder
Conforms
Solubility
Practically insoluble in water,very soluble in alcohol,in methanol ,in acetone,and in chloroform;slightly soluble in ethyl acetate.
Conforms
Identification
IR
UV
HPLC
sample IR spectrum corresponds to that of the standard
sample UC spectrum does not differ form that of the standard by more than 3.0%
retention time corresponds to that of the standard

Conforms

Conforms

Conforms
Residual on ignition
Not more than 0.5%
0.01%
Chromatographic purity
2-[3-(2methylpropyl)phenyl]propanoic acid:not more than 0.15%
2-(4-methylphenyl)propanoic acid:not more than 0.15%
2-(4-ethylphenyl)propanoic acid:not more than 0.15%
2-(4-propylphenyl)propanoic acid:not more than 0.15%
2-(4-butylphenyl)propanoic acid:not more than 0.1%
Any unknown impurity:not more than 0.05%
Total impurities:not more than 0.6%
0.06%

Not detected
0.02%
0.01%
Not detected
0.02%
0.12%
4-isobutylacetophenone
Not more than 0.1%
Not detected
Water content
Not more that 1.0%
0.12%
Heavy Metals
Not more than 0.002%
<0.002%
Residual solvents(petroleum ether)
Not more than 250ppm
55ppm
Assay(dry basis)
97.0-103.0%
99.50%
Bulk density
0.20-0.50g/ml
0.29g/ml
Tapped density
0.40-0.70g/ml
0.50g/ml
Median particle size
30-60um
37.9um
Conclusion
Comply with USP32