Pharmaceutical Products

High Purity Everolimus for Research
(CAS: 159351-69-6)

Details:
Drug Type: Everolimus is a targeted therapy and is classified as an mTOR inhibitor.
Everolimus CAS 159351-69-6 Brand: NEWBIO
MW: 958.22 MSDS: Inavaiable
MF:C53H83NO14 Sample: Avaiable
Category: API Min order: 10grams
Quality standard: 99.50% HPLC Place of Origin:China
Appearance Everolimus is a macrolide derived from Rapamycin (sc-3504) and shown to inhibit cell proliferation induced by growth factors. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Studies indicate that Everolimus is a mTOR (FRAP) inhibitor that displays high affinity toward the intracellular receptor FKBP12. Additionally, the Everolimus-FKBP12 complex decreases the activity of the S6K1 and 4EBP by binding to FRAP.
Applications Pharmaceutical raw materials An inhibitor of FRAP (mTOR)

What Everolimus Is Used For:
1) Treatment of advanced renal cell cancer, after sunitinib and sorafenib treatment failure.
2) Advanced pancreatic neuroendocrine tumors
3) Treatment of advanced hormone receptor positive, HER2negative breast cancer in post menopausal women, after treatmentfailure.

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