Rubber & Products

Ethyl 4 Aminobenzoate Active Pharmaceutical Ingredients 165.192 G / Mol

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Benzocaine

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Chemical Names: Benzocaine; Ethyl 4-aminobenzoate; ; Ethyl aminobenzoate; Ethyl p-aminobenzoate; Americaine
CAS number: 94-09-7
Molecular Formula: C9H11NO2
Molecular Weight: 165.192 g/mol


Benzocaine is a local anesthetic (numbing medication). It works by blocking nerve signals in your body.

Benzocaine topical is used to reduce pain or discomfort caused by minor skin irritations, sore throat, sunburn, teething pain, vaginal or rectal irritation, ingrown toenails, hemorrhoids, and many other sources of minor pain on a surface of the body. Benzocaine is also used to numb the skin or surfaces inside the mouth, nose, throat, vagina, or rectum to lessen the pain of inserting a medical instrument such as a tube or speculum.

There are many brands and forms of benzocaine topical available and not all brands are listed on this leaflet.

Benzocaine topical may also be used for purposes not listed in this medication guide.

What is the most important information I should know about benzocaine topical?

Benzocaine topical used in the mouth or throat may cause methemoglobinemia (met-HEEM-oh glo-bin-EE-mee-a), a life-threatening condition in which the amount of oxygen in your blood stream becomes dangerously low. Do not use benzocaine topical if you have ever had methemoglobinemia.

Pharmacodynamics: Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter analgesic ointments. It is also indicated for general use as a lubricant and topical anesthetic on intratracheal catheters and pharyngeal and nasal airways to obtund the pharyngeal and tracheal reflexes; on nasogastric and endoscopic tubes; urinary catheters; laryngoscopes; proctoscopes; sigmoidoscopes and vaginal specula.
Mechanism of action: Benzocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses.

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