Erlotinib Hydrochloride - Erlotinib Hydrochloride

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Erlotinib Hydrochloride

Small Molecular Erlotinib Hydrochloride
(CAS No.: 183319-69-9)

Chemical Information
Product Name Erlotinib hydrochloride
Molecular Formula C22H24ClN3O4
Molecular Weight 429.91


CAS 183319-69-9

CAS 183319-69-9 Brand: NEWBIO
MF C22H24ClN3O4 EINECS:ND
MW??429.9 MOQ: 100grams
Product Categories: API;Molecular Targeted Antineoplastic;Heterocyclic Compounds;anti-neoplastic;Heterocycles;Intermediates &?Fine Chemicals;Pharmaceuticals
Usage Erlotinib hydrochloride (trade name Tarceva) is a?drug used to treat non-small cell lung cancer (NSCLC), pancreatic cancer and several other types of cancer. It is a?reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR). It is marketed in the United States by Genentech and OSI Pharmaceuticals and elsewhere by Roche.
Applications Erlotinib hydrochloride ,?Pharmaceutical raw materials?

Description
Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2?nM in cell-free assays, >1000-fold more sensitive for EGFR than human c-Src or v-Abl.
?Erlotinib HCl (1 μM) induces apoptosis in DiFi humancolon cancer cells. Erlotinib inhibits growth of a?panel of NSCLC cell lines including A549, H322, H3255, H358 H661, H1650, H1975, H1299, H596 with IC50 ranging from 29 nM to >20 μM. Erlotinib HCl(2 μM) significantly inhibits growth of AsPC-1 and BxPC-3 pancreatic cells.?

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Wuhan Newbio Pharm-tech Co., Ltd.

Address: 858, East Lake, High-Tech Development Zone, Wuhan, Hubei, China, Wuhan, Hubei, China, 430075
Tel: 13277093700
Wuhan Newbio Pharm-Tech Co., Ltd., founded in 2015, is specialized manufacturer and supplier of Pharmaceutical Raw Materials and Pharmaceutical Intermediates. The company engages in pharmaceuticals R&D, production and sales. Our main products are Antibiotics, Small-molecule APIs, Novel Compounds, Fine Chemicals etc. The scientific research and innovation is our core value. The main direction of our research is chemicals R&D and the development of new method of synthesis. The company holds the belief of "Focus on research and development, bring benefit to human health", with the vision to develop a online platform for supplying and buying biological pharmaceutical raw materials. Thus if you have the same mission like us, we warmly welcome international cooperation.

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