Dapoxetine hydrochloride 119356-77-3 treatment of PE - 119356-77-3

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Dapoxetine hydrochloride 119356-77-3 treatment of PE

Dapoxetine hydrochloride 119356-77-3 treatment of PE

Product Name: Dapoxetine hydrochloride
Synonyms: DAPOXETIN;DAPOXETINE;(S-(+)-N,N-Dimethyl-a-[2-(naphthalenyloxy)ethyl]benzenemethanamine hydrochloride;Dapoxetine hydrochloride;Dapoxetine base;(S)-N,N-DiMethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-aMine;(S-(+)-N,N-DiMethyl-a-[2-(naphthalenyloxy)ethyl]benzeneMethanaMine hydrochloride Dapoxetine hydrochloride;D-Dapoxetine HCL
CAS: 119356-77-3
MF: C21H23NO.ClH
MW: 341.88
Product Categories: Erectile Dysfunction;API;Dapoxetine hydrochloride


Description

Dapoxetine (dapoxetine) as a new fasta selective 5 - HT reuptake inhibitor (SSRI), a short half life, , for the treatment of premature ejaculation and erectile dysfunction.

Dapoxetine, marketed as Priligy (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18-64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin& acute;s action at the post synaptic cleft, and as a consequence promoting ejaculatory delay.

As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.

Specifications

ITEMS STANDARD RESULTS
Characteristics White or almost white crystalline powder White crystalline powder
Melting point 175.0~177.0oC 174.0~179.0oC
Specific rotatlon +128°±3(C=1,CH3OH) +128°±3(C=1,CH3OH)
Loss on drying ≤0.5% 0.32%
Heavy metals 0ppm 0ppm
Relative substance ≤0.1%
Total impurity 0.07%
Assay(on drled basis) ≥99.5% 99.61%
Conclusion It complies to prescrlbed enterprise standard


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