Bio-technology Products

Creative Biolabs provides a large number of pre-formatted and customized human tissue microarrays to facilitate the use of this efficient but resource-demanding technique in basic and translational research. In addition, custom services, including IHC, ISH and FISH staining of the tissue microarrays, are available at the lowest price in industry.

Tissue microarray is a high-throughput technique that allows rapid gene expression and copy-number surveys of large numbers of different tissue specimens. In addition, it represents a technical revolution for highly effective use of human tissue specimens, which are both difficult and expensive to obtain in enough amount and case number.

Tissue microarrays are usually produced by re-locating tissues from conventional histological blocks. Typically, 40 to 1,000 cylindrical formalin-fixed and paraffin-embedded tissue cores can be densely and precisely arrayed into a single paraffin block. From the block, up to 300 serial 4-8 μm thick sections can be produced and placed on individual glass microscopic slides. Tissue microarray enables parallel in situ detection of DNA, RNA, or protein targets in each specimen on an array at cellular and tissue levels; at the same time, the large number of available consecutive arrays allows rapid analysis of multiple molecular markers in the same set of specimens. Essentially the same tests performed on conventional histological samples including H&E staining, immunohistochemistry and in situ hybridization can be done separately, or in parallel, on tissue microarrays.