Candesartan Cilexetil , China Candesartan Cilexetil Supplier

Candesartan Cilexetil - CAS No.: 145040-37-5

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Quick Details:
Product Name: Candesartan Cilexetil
CAS No.: 145040-37-5
MF: C33H34N6O6
MW: 610.66
Specification: CP, USP
Appearance: White to off-white crystalline powder.
Usage: Ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive.

Description:
Candesartan Cilexetil is a synthetic, benzimidazole-derived angiotensin II receptor antagonist prodrug with antihypertensive activity. After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal absorption, candesartan selectively competes with angiotensin II for the binding of the angiotensin II receptor subtype 1 (AT1) in vascular smooth muscle, blocking angiotensin II-mediated vasoconstriction and inducing vasodilatation. In addition, antagonism of AT1 in the adrenal gland inhibits angiotensin II-stimulated aldosterone synthesis and secretion by the adrenal cortex; sodium and water excretion increase, followed by a reduction in plasma volume and blood pressure.

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Taizhou Tianrui Pharmaceutical Co.,Ltd

Address: No.168,Xingtai Street,Jiaojiang Zone, Taizhou City, Zhejiang 318000, Taizhou City, Zhejiang , China, 318000
Tel: +86-(576)-88201638
Taizhou Tianrui Pharmaceutical Co., Ltd is established in 2005, engaging in the production and sale of APIs and their intermediates. It is located in the east coast of Zhejiang province, named Taizhou city, which is well known as raw chemicals production base at national level. Our company is currently holding stocks of three production factories that specialized in Anti-tuberculous, Anti-hypertensive, Anti-hyperlipidemic, Anti-bacterial, and Vitamin derivatives APIs and their intermediates productions. With our own import and export license, we are able to provide products complying with GMP and ISO9001. We have obtained several innovative and modified production skills from the cooperation with reputable clients and universities for years. Now we are able to produce high quality of APIs and their intermediates, such as Ivermectin, Eprinomectin, Rifaximin, Sodium Stearyl Fumarate, Irbesartan, Valsartan, R-2-Amino-1-Butanol etc. We have now received favorable reception from local and global customers by providing stable quality of products and our honesty, thus we have maintain a very strong role in the market. Some of our main products鈥?production skills are ranked highly among other companies, and we have even registered copyrights on them.