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99% Tibolone Acetate Livial 5630-53-5 Estrogen Muscle Gainning

Details:
CAS: 5630-53-5
EINECS: 227-069-1
Molecular Formula: C21H28O2
Molecular weight: 312.45
Melting Point: 169°C
Character: White powder.
Delivery: Express courier.
Usage: Pharmaceutical material

Description
General description
Tibolone is a synthetic steroid with weak estrogenic, androgenic, and progestogenic activity used in the treatment of menopausal syndrome. Tibolone and its metabolites induce prolactin production in human endometrial stromal cells in vitro.[] Sulfation plays a major role in the metabolism and regulation of the tissue-specific activity of tibolone and its metabolites.[]
Biochem/physiol Actions
Tibolone is a selective tissue estrogenic activity regulator (STEAR) used for the treatment of the symptoms associated with menopause and also for the treatment of osteoporosis. Tibolone has estrogenic, progestogenic, and/or androgenic activity depending on the tissue. Three major metabolites of tibolone are responsible for its tissue selective mechanism of action. Conversion into 3α- and 3β-hydroxy-tibolone results in estrogenic effects in brain, vagina, and bone. The Δ4 isomer has progestrogenic and androgenic effects and does not cause estrogenic stimulation in the endometrium.