Arimidex Anastrozole Powder Hair Loss Treatment Anti Estrogen Steroids - 120511-73-1
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Arimidex Anastrozole Powder Hair Loss Treatment Anti Estrogen Steroids
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Quick Detail:
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Product name | Anastrozole |
Other name | Arimidex |
CAS register number | 120511-73-1 |
Molecular formula | C17H19N5 |
Molecular weight | 293.37 |
Molecular structure | |
appearance | White powder |
Assay | 99% |
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Description:
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Anastrozole (INN) (marketed under the trade name Arimidex by AstraZeneca) is a non-steroidal aromatase-inhibiting drug approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and post-menopausal women.
Anastrozole is a drug used to treat breast cancer after surgery. Anastrozole is aromatase inhibitor.Anastrozole inhibits the enzyme aromatase,Anastrozole binds reversibly to the aromatase enzyme through competitive inhition .Anastrozole can be used in man and woman. Arimidex is the aromatase inhibitor of choice. Arimidex& acute;s mechanism of action — blocking conversion of aromatizable steroids to estrogen
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What is anastrozole used for:
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Anastrozole (INN) is a non-steroidal aromatase-inhibiting drug approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and post-menopausal women. The severity of breast cancer can be increased by estrogen, as sex hormones cause hyperplasia, and differentiation at estrogen receptor sites. Anastrozole works by inhibiting the synthesis of estrogen.
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Specifications:
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COA:
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Items | Standard | Results |
Description | White crystalline powder | Complies |
Identification | IR HPLC Reactive | Conform with standard IR Conform with standard HPLC Conform |
Solubility | Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile | Complies |
Total Impurity | max.0.5% | 0.18% |
Total Unspecified Impurity | max. 0.2% | 0.08% |
Individual unspecified impurlty | max. 0.1% | 0.05% |
Related compound B | max. 0.2% | 0.07% |
Related compound C | max. 0.2% | 0.04% |
Related compound D | max. 0.1% | 0.05% |
Related compound E | max. 0.1% | 0.06% |
Limit of cyclohexane | max. 0.08% | ND |
Limit of ethylacetate | max. 0.1% | 0.07% |
Melting point | 81.0~84.0℃ | 82.5～83.2℃ |
Water | max. 0.3% | 0.21% |
Residue on ignition | max. 0.1% | 0.07% |
Heavy Metals | max.0.001% | Complies |
Assay(HPLC) | 98.0%～102.0% | 99.8% |
Storage | Cool and dry |
Conclusion | It complies to USP32 . |
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HPLC:
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Shenzhen RuiJin Pharmaceutical Co.,Ltd
Address: B area, DongXing industrial area, panyu area, Guangzhou, China(Mainland), Guangzhou, Guangdong, China, 510000
Tel: 86-182-67623770
Shenzhen RuiJin Pharmaceutical Co.,Ltd a leading supplier of fine chemical in China, is located in Guangzhou. The unique geographical conditions of Guangzhou are favorable for transportation.The company invests large fund and brains to R&D department to research fine chemical,biochemical,pharmaceutical & its intermediates products that fit the demand of the market. High level research group, advanced apparatus and good scientific atmosphere ensure the quality.
