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AMPICILLIN 500?MG?Capsules
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COMPOSITION:
Each capsule contains?ampicillin?trihydrate equivalent to 500?mg ampicillin.
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PHARMACOLOGICAL?ACTION:
Ampicillin?is a bactericidal broad spectrum penicillin.
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INDICATIONS:
Infections due to susceptible organisms.
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CONTRA-INDICATIONS:
Ampicillin?should not be given to patients known to be allergic to penicillin nor, in the neo-natal period, to babies born of hypersensitive mothers.
Ampicillin?should not be given to patients with infectious mononucleosis since they are especially susceptible to ampicillin-induced rashes, patients with lymphatic leukaemia and patients with hyperuricaemia being treated with allopurinol, since they may be at increased risk of developing ampicillin-induced skin rashes.
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WARNINGS:
Ampicillin?may cause reactions typical of penicillin allergy. In patients with a history of penicillin or cephalosporin allergy?Ampicillin?should be used with caution.
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DOSAGE?AND?DIRECTIONS?FOR?USE:
Adults: ? ? ? ? ? ? ? ??250?mg to 750?mg every 6 hours.
Children 0 - 6 years: ??62,5?mg to 187,5?mg every 6 hours.
Children 7 - 10 years: ?125?mg to 375?mg every 6 hours.
Children over 10 years:?250?mg to 750?mg every 6 hours.
In severe infections doses may be increased or high doses administered parenterally.Ampicillin?should be taken 30 minutes to 1 hour before meals. In patients with renal impairment dosage may be reduced if required.
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SIDE?EFFECTS?AND?SPECIAL?PRECAUTIONS:
Overgrowth of non-susceptible organisms (Aerobacter aerogenes, Pseudomonas, Candida, etc.) may occur and under these circumstances,?Ampicillin?treatment should be discontinued and specific or supportive therapy instituted. Diarrhoea, nausea, vomiting, heartburn and pruritis ani may occur. When?Ampicillin?is administered to a hypersensitive patient, allergic reactions may occur. Urticaria and maculopapular skin rashes are common, exfoliative dermatitis, eosinophilia, angioneurotic oedema, erythema multiforme, fever and swollen joints may occur.
Allergic reactions which may be fatal such as anaphylaxis may occur. These reactions may be common after parenteral use but may also occur after oral administration. If serious anaphylactic reaction occurs,?Ampicillin?should be discontinued and the patient treated with adrenalin, corticosteriods and antihistamines. The onset of the symptoms varies: it may occur within a few days of the beginning of treatment or not until therapy with a penicillin derivative is resumed on a subsequent occasion. In cases of ampicillin treatment of mononucleosis a rash usually appears. Severe pseudomembranous colitis may occur. Raised serum aminotransferase concentrations have been reported.
Use with caution in patients with syphylis as the Jarish-Herxheimer reaction may occur.
STORAGE?INSTRUCTIONS:
Store?below?25°C.?Protect?from?moisture.
KEEP?OUT?OF?REACH?OF?CHILDREN.
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ZHEJIANG MEDICINES&HEALTH PRODUCTS I/E CO.,LTD
Address: 101-2, N. Zhongshan Road, Hangzhou, Zhejiang, China (Mainland), Hangzhou, Zhejiang, China, 310000
Tel: 86-571-28935880
Zhejiang Medicines and Health Products Import &Export Co., Ltd (ZMC) is a subsidiary of Zhejiang International Business Group Co., Ltd. ZMC has evolved from a former state-owned enterprise in 1999 into a shareholding company with modern corporate governance structure and has been listed ever since 1990 among the top 500 exporters of China for 16 consecutive years.
Through incessant efforts over the years on the exploitation for new and high quality products that help better meet our customers鈥?needs and strengthen the competitiveness, our export revenue in 2014 hit a record high of USD 589 millions,and listed among the top 5 export of pharmacetical formulations in China,2013 and 2014.
We have established extensive and pleasant working ties with numerous manufacturers within China on a long-term basis and enjoyed a reliable marketing network in over 100 countries and regions in Asia, Europe, America, Africa and Oceania.
In recent years, according to the needs of our business development, extension of supply chain and strategic objectives, ZMC has invested in over 10 related manufactures in the form of share holding or share purchasing, thus boosting the marketing abroad for the related export products