314728-85-3 Sunifiram Anabolic Steroid Powder for Memory Enhancement - 314728-85-3
314728-85-3 Sunifiram Anabolic Steroid Powder for Memory Enhancement For Sale, Most Competitive Price, Fast Delivery, Custom Service, Wholesale 314728-85-3 Sunifiram Anabolic Steroid Powder for Memory Enhancement, Made in China, High Quality Products!, China SARMs, chemical Supplier, Manufacturer.
Sunifiram Anabolic Steroid Powder for Memory Enhancement
Basic Info:
CAS: 314728-85-3
MF: C14H18N2O2
MW: 246.30492
Appearance: White powder
Purity: 99.32%
Shelf life: 2 years
Standard: In-house Standard
Usage: For the treatment of Alzheimers Dementia, Cognition Disorder, Neurologic Drugs, Senile Dementia, Acetylcholine Release Enhancers.
Product Description:
This compound is known as an AMPAkine due to exerting most of its actions via the AMPA receptor (one of the three main subsets of glutamate receptors, alongside NDMA and kainate). This enhancement of AMPA function seems to also rely on enhancing signalling via the Glycine binding site of NMDA receptors, although one minimal signalling goes through the NMDA receptor then the benefits on AMPA receptors seem dose-dependent.
Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232).
This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation.Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.
Application:
For the treatment of Alzheimers Dementia, Cognition Disorder, Neurologic Drugs, Senile Dementia, Acetylcholine Release Enhancers.
Sunifiram (DM-235) is a synthetic derivative of Piracetam, although due to breaking the pyrrolidone backbone it is no longer in the Racetam class of drugs (yet by being derived from them, it is still commonly associ
Guangzhou Kafen Biotech Co., Ltd.
Address: No. 128, Hanxing East Rd, Zhongcun, Panyu District,, Guangzhou, GuangDong, China, 511495
Tel: +8618022403273
Guangzhou Kafen Biotech Co., Ltd is a high-tech and professional company founded in 2002, which specialized in developing, manufacturing, distributing steroid hormone powders and intermediates. We have been devoted in R&D, production and marketing steroid hormone and pharmaceutical raw materials.
With advanced production technology and equipment, strong technical force, first-class laboratory and inspection equipment. Kafen has developed into a professional factory manufacturing anabolic steroid powders with several years'efforts and contribution of experienced technicians in different areas. Company affiliated factory has advanced production equipment and plants, perfect quality assurance and control system, whole set of High Pressure Liquid Chromatography/Gas Chromatography/UV Spectrophotometer to conduct effective product analysis and monitoring. Company factory has passed ISO9001 quality system certification and international KOSHER certification.
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