10-hydroxycamptothecin - STA-06

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10-hydroxycamptothecin

Product Name: 10-hydroxycamptothecin

Synonym: Spyrano[3, 4: 6, 7]indolizino[1, 2-b]quinoline-3, 14(4H, 12H)-dione

Molecular Formula: C20H16N2O5

Formula Weight: 364.35

CAS No. 19685-09-7 ,7689-03-4

Botanical source: Camptotheca acuminata Decne

Appearance: Light Yellow Crystal Powder

Odor: Characteristic

Solubility: Insoluble in water, its sodium salt is the water-soluble, its organic solution has blue fluorescence.


Specification: 10-hydroxycamptothecin >98%

Sieve analysis: 100% through 80 mesh

Storage: Store in cool & dry place, Keep away from strong light and heat.

Shelf life: 24Months when properly stored.

Packing: Aluminum foil-bag and two plastic-bags inside


Functions:

10-hydroxycamptothecin is the derivative of camptothecine that is a micro-alkaloid from camptotheca Acuminate (a tree native to mainland China). Is a kind of pharmaceutical intermediate, an alkaloid originally isolated from the Camptotheca acuminata, exerted inhibitory effects on DNA topoisomerase (Topo )[1]and has anticancer activity in vitro and in vivo. It can also induce differentiation of leukemia MELC[2]and HL-60[3]cells. The purpose of this study is to investigate the proliferation-inhibiting and differentiation-inducing actions of HCPT on human hepatoma Hep G2 cells.

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Address: No.186,Lugu Valley Garden Road, High-tech Development Zone, Changsha , Hunan, P.R. China(410205), Changsha, Hunan, China, 410205
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Changsha Staherb Natural Ingredients Co.,Ltd., a good supplier of professional herb extracts, especially those with high purity and standardized production process. Our company devotes to supply high quality products and services to customers in R&D and production fields of health products, cosmetics, feed additives and biopesticides. With cordial and professional R&D, sales and after sales service groups, Staherb has potent capabilities both in R&D and production. The company persists in high investment on R&D of active ingredients of plants and promotes innovation on demands of customers. Upon constant R&D and tracing of new technologies and new products, Staherb makes effective cooperation with famous research institutes, such as CAS Kunming Institute of Botany, State Key Lab of Hunan Forest Products and Chemical Engineering, Hunan Agricultural University and so on.. Now the main products of Staherb are standardized high purity plant extracts, including Epimedium (10-98%), Eucommia leaf Extract (5-95%) amygdalin (50-98%), Ursolic acid (25-98%),and Corosolic acid (1-98%). In order to meet customers鈥檙esearch needs, our company also provides over 600 plant extracts, most of which are high-purity monomer plant compounds and reference substance. And some products can be supplied with milligram-scale, kilogram-scale or even to ton-scale. In addition, based upon the powerful R&D capability, Staherb can provide both products customization services and R&D outsourcing services according to customers specific requirements, so that to meet their continual innovation needs in the fields of natural productsdiscovery and production.

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