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Cediranib maleate

857036-77-2

Description

Cediranib (AZD2171) maleate is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3.

Cediranib maleate, 857036-77-2,

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agonist,antagonist,inhibitor,kinase inhibitors, tyrosine kinase inhibitors, enzyme inhibitors,Drug-like molecules

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