Pharmaceutical Chemicals
Description
MK-677/Ibutamoren
EMAIL: cgf at chembj dot com
Skype: cgf@chembj.com
Whatsapp: +8615564141272
CAS: 159752-10-0
MF: C27H36N4O5S.CH4O3S
MW: 624.776
Purity: >99% (HPLC analyzed).
Apperance: Pale Yellow Solid
Certification: GMP, HSE, ISO 9001, USP, BP
Storage: Storage; Store at -20°C
Standard: Enterprise standard
Usage: It is a potent and tissue-selective androgen receptor modulator (SARM)
Description:
Nutrobal (Mk-677) is an orally administrated growth hormone secretagogue originally developed by Reverse Pharmacology. A secretagogue is the term for a substance that chemically signals for the pituitary gland to secrete growth hormone. In other words, Nutrobal could be compared to peptides likeGHRP-6 or Ipamorelin, only it doesn& acute;t require any injections nor does it have any side effects like GHRP-6. This GHS (Growth Hormone Secretagogue) was developed in an aim to combat such conditions as muscle wasting, obesity and osteoporosis. It was also targeted towards treatment of elderly hip fracture patients, so there are a myriad of studies done on safety.
Growth hormone pulse intensity can be increased through 4 possible mechanisms:
Increasing GHRH (growth hormone releasing hormone) release.
Amplifying GHRH signaling in somatotrophs of the anterior pituitary gland.
Reducing somatostatin release (somatostatin turns off GH release).
Inhibiting of somatostatin receptor signaling.
Nutrobal (Mk-677) was found to work through all four of these mechanisms.
After ingestion, Growth Hormone (GH) was shown to increase dose dependently, at doses starting at 5 milligrams (mgs) a day.
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Jinan Jia Ge Biological Technology Co, Ltd
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Address: No 28, Sankongqaio street, Tianqiao district, Jinan,
Jinan, Shandong
China,
Tel: 86-15564141272
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